منابع مشابه
CPT: Pharmacometrics and Systems Pharmacology
Welcome to the first issue of CPT: Pharmacometrics and Systems Pharmacology (CPT:PSP), a new journal from the American Society for Clinical Pharmacology and Therapeutics. CPT:PSP is a cross-disciplinary journal devoted to publishing advances in quantitative, model-based approaches as applied in pharmacology, (patho)physiology, and disease to aid the discovery, development, and utilization of hu...
متن کاملCPT: Pharmacometrics & Systems Pharmacology
QSP-10 APPLICATION OF AN IN SILICO PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL TO SIMULATE ORAL DRUG BIOAVAILABILITY OF ATORVASTATIN ACID AND CYCLOSPORINE POST BARIATRIC SURGERY. A. S. Darwich,1 D. Pade,2 K. Rowland-Yeo,2 M. Jamei,2 A. Åsberg,3 H. Christensen,3 D. M. Ashcroft,1 A. Rostami-Hodjegan1; 1Centre for Applied Pharmacokinetic Research, University of Manchester, Manchester, United Kingd...
متن کاملAdvancing pharmacometrics and systems pharmacology.
Pharmacometrics and systems pharmacology are emerging as principal quantitative sciences within drug development and experimental therapeutics. In recognition of the importance of pharmacometrics and systems pharmacology to the discipline of clinical pharmacology, the American Society for Clinical Pharmacology and Therapeutics (ASCPT), in collaboration with Nature Publishing Group and Clinical ...
متن کاملPharmacometrics: Focus on the Patient
Pharmacometrics, whether using simple or complex models, has contributed to rational and efficient drug development,(1-3) with the main focus on early drug development.(4) This article describes why opportunities more directly focused on the patient abound in late stage development, illustrating the concept with three innovative examples which focus on benefits to patients, enabling drugs that ...
متن کاملThe status of pharmacometrics in pregnancy: highlights from the 3rd American conference on pharmacometrics
Physiological changes during pregnancy may alter drug pharmacokinetics. Therefore, mechanistic understanding of these changes and, ultimately, clinical studies in pregnant women are necessary to determine if and how dosing regimens should be adjusted. Because of the typically limited number of patients who can be recruited in this patient group, efficient design and analysis of these studies is...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1998
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.29.565